Structure of PDB 6r1u Chain A

Receptor sequence
>6r1uA (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB6r1u A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
ChainA
Resolution4.36 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A H39 Y41 T45 R72 R83 F84 R116 V117 T118 H3 Y5 T9 R36 R47 F48 R80 V81 T82
BS02 dna A R40 Y41 R42 V46 R49 R63 K64 L65 R69 R83 R4 Y5 R6 V10 R13 R27 K28 L29 R33 R47
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:6r1u, PDBe:6r1u, PDBj:6r1u
PDBsum6r1u
PubMed30970244
UniProtP84233|H32_XENLA Histone H3.2

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