Structure of PDB 6r0t Chain A

Receptor sequence
>6r0tA (length=159) Species: 59300 (Getah virus) [Search protein sequence]
APSYRVRRADISGHGEEAVVNAANAKGTVSDGVCRAVAKKWPSSFKGAAT
PVGTAKMIRADGMTVIHAVGPNFSTVTEAEGDRELAAAYRAVASIISTNN
IKSVAVPLLSTGTFSGGKDRVMQSLNHLFTALDATDADVVIYCRDKNWEK
KIQEAIDRR
3D structure
PDB6r0t Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JNT A D10 I11 A22 N24 S30 D31 G32 V33 C34 L108 S110 T111 G112 T113 F114 R144 W148 D10 I11 A22 N24 S30 D31 G32 V33 C34 L108 S110 T111 G112 T113 F114 R144 W148
External links
PDB RCSB:6r0t, PDBe:6r0t, PDBj:6r0t
PDBsum6r0t
PubMed32879358
UniProtQ5Y389|POLN_GETV Polyprotein P1234

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