Structure of PDB 6r0r Chain A

Receptor sequence
>6r0rA (length=162) Species: 59300 (Getah virus) [Search protein sequence]
MKAPSYRVRRADISGHGEEAVVNAANAKGTVSDGVCRAVAKKWPSSFKGA
ATPVGTAKMIRADGMTVIHAVGPNFSTVTEAEGDRELAAAYRAVASIIST
NNIKSVAVPLLSTGTFSGGKDRVMQSLNHLFTALDATDADVVIYCRDKNW
EKKIQEAIDRRT
3D structure
PDB6r0r Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography.
ChainA
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
3.1.3.84: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.1.74: mRNA 5'-phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JNT A D10 I11 A22 N24 S30 G32 V33 C34 S110 T111 G112 T113 F114 W148 D12 I13 A24 N26 S32 G34 V35 C36 S112 T113 G114 T115 F116 W150
External links
PDB RCSB:6r0r, PDBe:6r0r, PDBj:6r0r
PDBsum6r0r
PubMed32879358
UniProtQ5Y389|POLN_GETV Polyprotein P1234

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