Structure of PDB 6qzj Chain A

Receptor sequence
>6qzjA (length=245) Species: 9606 (Homo sapiens) [Search protein sequence]
VREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVH
VAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSL
FYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQ
LCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPP
RIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGS
3D structure
PDB6qzj Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOL A V82 G90 V49 G57
BS02 GOL A R106 F187 D191 R73 F154 D158
BS03 GOL A L162 D164 G250 E251 L129 D131 G217 E218
BS04 GOL A F74 G222 Y223 A224 R229 F41 G189 Y190 A191 R196
Gene Ontology
Molecular Function
GO:0015267 channel activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6qzj, PDBe:6qzj, PDBj:6qzj
PDBsum6qzj
PubMed31831212
UniProtO14520|AQP7_HUMAN Aquaporin-7 (Gene Name=AQP7)

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