Structure of PDB 6qlr Chain A

Receptor sequence
>6qlrA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB6qlr Structure and Energetics of Ligand-Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions.
ChainA
Resolution0.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 J4N A R144 I145 A146 H158 R162 W181 E184 S237 R32 I33 A34 H46 R50 W69 E72 S125 MOAD: Kd=8.8uM
PDBbind-CN: -logKd/Ki=4.82,Kd=15uM
BindingDB: Kd=15000nM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:6qlr, PDBe:6qlr, PDBj:6qlr
PDBsum6qlr
PubMed31246331
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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