Structure of PDB 6qjx Chain A

Receptor sequence
>6qjxA (length=195) Species: 562 (Escherichia coli) [Search protein sequence]
SRLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRAL
LDALAVEILARHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHL
GARPDEKQYDTVETQLRFMTENGFSLRDGLYAISAVSHFTLGAVLEQQEH
TNLPPLLREALQIMDSDDGEQAFLHGLESLIRGFEVQLTALLQIV
3D structure
PDB6qjx Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MIY A H64 S67 N82 F86 H100 Q116 L131 S135 S138 H139 H63 S66 N81 F85 H99 Q115 L130 S134 S137 H138
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:6qjx, PDBe:6qjx, PDBj:6qjx
PDBsum6qjx
PubMed32114262
UniProtP0ACT4|TETR4_ECOLX Tetracycline repressor protein class D (Gene Name=tetR)

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