Structure of PDB 6qgh Chain A

Receptor sequence
>6qghA (length=154) Species: 9606 (Homo sapiens) [Search protein sequence]
QDNREIVMKYISYKLSQRGYEWESEVVHQTLRQAGDDFSLRYRRDFAEMS
SQLHLTPGTAYASFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREM
SVLVDNIAAWMATYLNDHLHTWIQDNGGWDAFVELYGNNAAAESRKGQER
FLEH
3D structure
PDB6qgh Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1XJ A A100 Y108 D111 W144 G145 R146 F198 L201 Y202 N204 E209 A34 Y42 D45 W78 G79 R80 F132 L135 Y136 N138 E143
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:6qgh, PDBe:6qgh, PDBj:6qgh
PDBsum6qgh
PubMed31459977
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2);
Q07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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