Structure of PDB 6qf4 Chain A

Receptor sequence
>6qf4A (length=287) Species: 9606 (Homo sapiens) [Search protein sequence]
ENLYFQSMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKR
RRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGE
IFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLS
SIYPLGDIKIVDFGMSRKIGHACIMGTPEYLAPEILNYDPITTATDMWNI
GIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQ
SLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETS
3D structure
PDB6qf4 On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies.
ChainA
Resolution2.495 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D158 K160 Q162 N163 D179 T198
Catalytic site (residue number reindexed from 1) D141 K143 Q145 N146 D162 T177
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A N163 D179 N146 D162
BS02 ADP A A60 K62 A113 E117 L165 D179 A43 K45 A96 E100 L148 D162
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6qf4, PDBe:6qf4, PDBj:6qf4
PDBsum6qf4
PubMed31316815
UniProtO94768|ST17B_HUMAN Serine/threonine-protein kinase 17B (Gene Name=STK17B)

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