Structure of PDB 6qe4 Chain A

Receptor sequence
>6qe4A (length=308) Species: 9606 (Homo sapiens) [Search protein sequence]
GAAWACFRLDGRTLLRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARA
GYAHFLNVQGRTLYDVILYGLQEHSEVSGFLLECDSSVQGALQKHLALYR
IRRKVTVEPHPELRVWAVLPSSPEACGAASLQERAGAAAILIRDPRTARM
GWRLLTQDEGPALVPGGRLGDLWDYHQHRYLQGVPEGVRDLPPGVALPLE
SNLAFMNGVSFTKGCYIGQELTARTHHMGVIRKRLFPVRFLDPLPTSGIT
PGATVLTASGQTVGKFRAGQGNVGLALLWSEKIKGPLHIRASEGAQVALA
ASVPDWWP
3D structure
PDB6qe4 In-house high-energy-remote SAD phasing using the magic triangle: how to tackle the P1 low symmetry using multiple orientations of the same crystal of human IBA57 to increase the multiplicity.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I3C A K248 T277 G279 K280 L292 W294 K233 T262 G264 K265 L277 W279
BS02 I3C A W188 Q192 N287 W173 Q177 N272
BS03 I3C A K119 V120 T121 K104 V105 T106
BS04 I3C A R158 D159 P160 T162 A163 G166 R143 D144 P145 T147 A148 G151
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0016740 transferase activity
Biological Process
GO:0006783 heme biosynthetic process
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

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Biological Process
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Cellular Component
External links
PDB RCSB:6qe4, PDBe:6qe4, PDBj:6qe4
PDBsum6qe4
PubMed30950402
UniProtQ5T440|CAF17_HUMAN Putative transferase CAF17, mitochondrial (Gene Name=IBA57)

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