Structure of PDB 6q8j Chain A

Receptor sequence
>6q8jA (length=188) Species: 9606 (Homo sapiens) [Search protein sequence]
EIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINS
GHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPM
IMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEV
SVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKA
3D structure
PDB6q8j Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XS4 A W56 D57 L60 Q61 Q64 Y77 A92 L96 W53 D54 L57 Q58 Q61 Y74 A89 L93
BS02 XS4 A A92 S95 A89 S92
Gene Ontology
Biological Process
GO:0000398 mRNA splicing, via spliceosome

View graph for
Biological Process
External links
PDB RCSB:6q8j, PDBe:6q8j, PDBj:6q8j
PDBsum6q8j
PubMed31076555
UniProtQ2TAY7|SMU1_HUMAN WD40 repeat-containing protein SMU1 (Gene Name=SMU1)

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