Structure of PDB 6q8e Chain A

Receptor sequence
>6q8eA (length=307) Species: 525904 (Thermobaculum terrenum ATCC BAA-798) [Search protein sequence]
ENPKYLWWNHRIIPWEEATVHLTDYWWASVTAVFEGIRGYWNNAEGEMYI
FRLEDHARRLEQSMQLIRMPKEFTVDEICQATIDLVRANDYRGDVYIMPL
AYAVGNKAFSVVGDRTTEMFIYSRPAVSRLEEDFSLHACYSSWTRINERV
LPPRIKALANYRNSQLASSEAAMNGYDTALFLNPEGKVAEGTGSCVFFVR
KGKLITPDITSGILESITRDTVIHLAREVLGLEVEERVVDRTETYLADEA
FLCGTHAEITPIASIDRHEMKHGAPGPITRQLRDIYREVVYGRDFRYRNW
LTPVGMG
3D structure
PDB6q8e Biochemical and structural insights into PLP fold type IV transaminase from Thermobaculum terrenum.
ChainA
Resolution1.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F39 K161 E195 L219
Catalytic site (residue number reindexed from 1) F34 K156 E190 L214
Enzyme Commision number 2.6.1.42: branched-chain-amino-acid transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PMP A R64 K161 Y166 E195 G198 S199 C200 L219 S221 I222 T223 G259 T260 R59 K156 Y161 E190 G193 S194 C195 L214 S216 I217 T218 G254 T255
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004084 branched-chain-amino-acid transaminase activity
GO:0008483 transaminase activity
GO:0052654 L-leucine-2-oxoglutarate transaminase activity
GO:0052655 L-valine-2-oxoglutarate transaminase activity
GO:0052656 L-isoleucine-2-oxoglutarate transaminase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009081 branched-chain amino acid metabolic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009098 L-leucine biosynthetic process
GO:0009099 L-valine biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6q8e, PDBe:6q8e, PDBj:6q8e
PDBsum6q8e
PubMed30599183
UniProtD1CCW1

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