Structure of PDB 6q63 Chain A

Receptor sequence
>6q63A (length=751) Species: 818 (Bacteroides thetaiotaomicron) [Search protein sequence]
QEEANYQIIPLPQEIVTSQVNPFILKSGVKILYPEGNEKMQRNAQFLADY
LKTATGKDFSIEAGTEGKNAIVLALGSEVENPESYQLKVTDQGVTITAPT
EAGVFYGIQTLRKSLPIALGADVALPAVEIKDAPRFGYRGAHFDVSRHFF
TIDEVKTYIDMLALHNMNRLHWHITDDQGWRLEIKKYPKLTEIGSQRSGT
VIGRNSGEYDNTPYGGFYTQEQAKEIVDYAAERYITVVPEIDLPGHMLAA
LAAYPELGCTGGPYEVWRQWGVADDVLCAGNDQVLKFLEDVYGELIEIFP
SEYIHVGGDECPKVRWEKCPKCQARIKALGLKSDKNHSKEERLQSFVINH
IEKFLNDHGRQIIGWDEILEGGLAPNATVMSWRGESGGIEAAKQKHDVIM
TPNTYLYFDYYQAKDTENEPFGIGGYLPMERVYSYEPMPASLTPDEQQYI
KGVQANLWTEYIATFSHAQYMVLPRWAALCEVQWSTPDKKNYEDFLSRLP
RLIKWYDAEGYNYAKHVFDVKAEFTPNPADGTLDITLTTIDNAPIHYTLD
GTEPTSTSPVYDGALKIKENADFSAIAIRPTGNSRVVSEKIDFSKSSMKP
IVANQPVNKQYEFKGVSTLVDGLKGNGNYKTGRWIAFRGNDMDVTIDLKQ
PTEISSVAISTCVEKGDWVFDTRGLSVEVSEDGTNFTKVASEAYPAMKET
DKNGVYDHKLTFTPVTAQYVKVIASPEKSIPEWHGGKSYPGFLFVDEITI
N
3D structure
PDB6q63 Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci.
ChainA
Resolution2.44 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D332 E333
Catalytic site (residue number reindexed from 1) D309 E310
Enzyme Commision number 3.2.1.52: beta-N-acetylhexosaminidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU A C282 C301 C342 C259 C278 C319
BS02 CA A T641 D644 L646 D769 E770 T618 D621 L623 D746 E747
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0030203 glycosaminoglycan metabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6q63, PDBe:6q63, PDBj:6q63
PDBsum6q63
PubMed31160824
UniProtA0A174QSL3

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