Structure of PDB 6q1u Chain A

Receptor sequence
>6q1uA (length=244) Species: 9606 (Homo sapiens) [Search protein sequence]
FDCGKPQVEPKKCPVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEW
VLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDI
ALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLL
KEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVC
FEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
3D structure
PDB6q1u Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides.
ChainA
Resolution2.3467 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) H603 D646 Q738 G739 D740 S741
Catalytic site (residue number reindexed from 1) H56 D99 Q191 G192 D193 S194
Enzyme Commision number 3.4.21.7: plasmin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F587 H603 D646 R719 S736 C737 Q738 G739 S741 S760 W761 G762 L763 F40 H56 D99 R172 S189 C190 Q191 G192 S194 S213 W214 G215 L216
BS02 peptide A P609 L638 L640 P62 L91 L93
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6q1u, PDBe:6q1u, PDBj:6q1u
PDBsum6q1u
PubMed32270580
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

[Back to BioLiP]