Structure of PDB 6q0q Chain A

Receptor sequence
>6q0qA (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNP
RFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKV
AVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB6q0q Linear triazole-linked pseudo oligogalactosides as scaffolds for galectin inhibitor development.
ChainA
Resolution1.98601 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 P8G A H158 R162 E165 W181 E184 H47 R51 E54 W70 E73 MOAD: Kd=535mM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:6q0q, PDBe:6q0q, PDBj:6q0q
PDBsum6q0q
PubMed32220037
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

[Back to BioLiP]