Structure of PDB 6pzd Chain A

Receptor sequence
>6pzdA (length=389) Species: 1332244 (Influenza A virus (A/Shanghai/02/2013(H7N9))) [Search protein sequence]
RRNFNNLTKGLCTINSWHIYGKDNAVRIGESSDVLVTREPYVSCDPDECR
FYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVHNSRVECIGWS
STSCHDGKSRMSICISGPNNNASAVVWYNRRPVAEINTWARNILRTQESE
CVCHNGVCPVVFTDGSATGPADTRIYYFKEGKILKWESLTGTAKHIEECS
CYGERTGITCTCRDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPN
DPNIGKCNDPYPGNNNNGVKGFSYLDGANTWLGRTISTASRSGYEMLKVP
NALTDDRSKPIQGQTIVLNADWSGYSGSFMDYWAEGDCYRACFYVELIRG
RPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL
3D structure
PDB6pzd Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
ChainA
Resolution1.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D293 G297 D324 N347 D214 G218 D245 N267
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0046761 viral budding from plasma membrane
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pzd, PDBe:6pzd, PDBj:6pzd
PDBsum6pzd
PubMed31757767
UniProtR4NFR6

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