Structure of PDB 6pyx Chain A

Receptor sequence
>6pyxA (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
ETGIGQRIVCLVLDKSGSMATGNRLNRLNQAGQLFLLQTVELGSWVGMVT
FDSAAHVQSELIQINSGSDRDTLAKRLPAAASGGTSICSGLRSAFTVIRK
KYPTDGSEIVLLTDGEDNTISGCFNEVKQSGAIIHTVALGPSAAQELEEL
SKMTGGLQTYASD
3D structure
PDB6pyx Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A S314 S316 T383 D412 S16 S18 T85 D114
External links
PDB RCSB:6pyx, PDBe:6pyx, PDBj:6pyx
PDBsum6pyx
PubMed31995732
UniProtA8K7I4|CLCA1_HUMAN Calcium-activated chloride channel regulator 1 (Gene Name=CLCA1)

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