Structure of PDB 6py0 Chain A

Receptor sequence

>6py0A (length=101) Species: 10090 (Mus musculus) [Search protein sequence]

RWVQFMKEAGQGSRDMWRAYSDMKKANWKNSDKYFHARGNYDAARRGPGG
AWAAKVISDAREAVQKFTGHGDSRADQFANEWGRSGKDPNHFRPAGLPKR
Y

3D structure

PDB

6py0 Molecular basis for retinol binding by serum amyloid A during infection.

Chain

Resolution

2.204 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	RTL	A	A79 A82 V83	A60 A63 V64	PDBbind-CN: -logKd/Ki=6.41,Kd=386nM

Gene Ontology

	Molecular Function
GO:0035662	Toll-like receptor 4 binding
GO:0042056	chemoattractant activity

	Biological Process
GO:0006953	acute-phase response
GO:0009617	response to bacterium
GO:0035634	response to stilbenoid
GO:0050918	positive chemotaxis
GO:0060326	cell chemotaxis
GO:0071347	cellular response to interleukin-1

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0034364	high-density lipoprotein particle

External links

PDB	RCSB:6py0, PDBe:6py0, PDBj:6py0
PDBsum	6py0
PubMed	31484771
UniProt	P04918\|SAA3_MOUSE Serum amyloid A-3 protein (Gene Name=Saa3)