Structure of PDB 6pxc Chain A

Receptor sequence
>6pxcA (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
TAPPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQ
MNVVNHFRIIAMSGDYYIGGRRFSSLSDLIGYYSHVSSLLKGEKLLYPVA
PPEP
3D structure
PDB6pxc Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R188 R207 R211 V217 H229 F230 R231 I241 Y256 S260 L262 R15 R34 R38 V44 H56 F57 R58 I68 Y83 S87 L89
External links
PDB RCSB:6pxc, PDBe:6pxc, PDBj:6pxc
PDBsum6pxc
PubMed31891593
UniProtP20936|RASA1_HUMAN Ras GTPase-activating protein 1 (Gene Name=RASA1)

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