Structure of PDB 6pvh Chain A

Receptor sequence

>6pvhA (length=444) Species: 70095 (Penicillium fellutanum) [Search protein sequence]

GEEVQVIIVGLGIVGLAAAIECREKGHSVHAFEKSNILKSIGDCIGLQSN
ATRIIKRWGDGAVHEALRPWIVSSKEIRIHNSSGRLIIRQDLSEVCEQPN
YLLPRSELIRVMYEHALKIGVEISLGVEVCEPSEDEEGASVVALTRDGER
QIVRGDFIICSDGVHSKMRKAIMPQPVEPRPSGYAAFRALVDTETLKGDP
EASWVFEGVEENDRFDVFFLSGAQIALQSCNKGKVFSWFCIHQDTRNLLD
VWTSPADPNEMLDLIKVWPIGQRLWSVIRHTQPQKFINYPLLNHKPLDHW
VSSHGRLILIGDAAHPLSPAAGQGASQGIEDANVLATSLSLAGRQRVSLA
LHVAERIRYARASAVQLISHRVNEGWRNQDWDAYEPNEQNIASLPLETWI
YGHDSQAYTEQEFEMVVRAVQEGEEYHATNLPDKLRVQLGIRNV

3D structure

PDB

6pvh Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.

Chain

Resolution

1.89 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.-.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	OZ4	A	L96 N104 F219 V221 F243 A324 G326 I395 A396 P399 L400	L92 N100 F215 V217 F239 A320 G322 I391 A392 P395 L396
BS02	FAD	A	G14 G16 I17 V18 E37 K38 I45 G46 D47 I49 R109 V133 D166 G167 W256 G315 D316 A329	G10 G12 I13 V14 E33 K34 I41 G42 D43 I45 R105 V129 D162 G163 W252 G311 D312 A325

Gene Ontology

	Molecular Function
GO:0004497	monooxygenase activity
GO:0071949	FAD binding

View graph for
Molecular Function

External links

PDB	RCSB:6pvh, PDBe:6pvh, PDBj:6pvh
PDBsum	6pvh
PubMed	31904957
UniProt	L0E4H0\|PHQK_PENFE FAD-dependent monooxygenase phqK (Gene Name=phqK)

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