Structure of PDB 6ppr Chain A

Receptor sequence
>6pprA (length=834) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence]
GVVRLLGPGTGKSSLLVDTAVQHILLTGSARLRTAARAAITARLTVHSYA
FAVLRLSAEQDGIIRELLAGDGWPEQLWPALTTAGFATELRDLMARCTER
GVDPIALQRLGRPEWLAAGRFAQAYEQILGAAELVGAALEALLLDTERNR
IKLLLVDDAQHLDPQAARLVRALALTVIAGDPDQSHPAITLTQSYRCAPE
IASAITGLGQWTGNPQREGTVTVRLAASTHAEGTMIADALRRAHLVDGIP
WSQMAVIVRSVPRVGTALARALTAAGVPVQDDVPVGRQPAAAALLTVLDV
TATGHLDADSAVALLTGPIGRVDPVTLRQLRRALRRADGSQPPRDFGDLL
VDAIEREPKGLSAEHARTLRRLRAVLTAARRDPRYTLWQAWHASGLQRRW
LAASERGGSVGAQADRDLDAVTTLFDVADQYVLRGLVDHVAVAVLSVHGA
LAGEWDFVVIAGVQEGLWPNMIPRGGVLGTQHLVDVLLVAEERRLLMAAM
GRARTRVMITAVDLLPSPFCAEISAWATEPPLVAPRVLAPSALVGRLRAV
VCAPDARACAAAQLARLAAAGVPGADPSQWHAMTSLTTEEPLWSEPGHVV
TLSPSTLQMLTDCPLRWLLERHGGDDGRDVRSTVGSLVHALVSEPGKTES
QLVNELEKVWDDLPYDAKWYSDNELARHRAMLETFTRWREDTRRQLTEVA
TEIPVEGIVVEPGVRVRGRLDRLERDEAGRLVVVALKTGKSPVTKDDAQN
HAQLAMYQLAVAAGLGDEPGGGKLVYLGKAGATEREQDPLTPDKRAEWLE
TVGEAAAATAGPRFVARVNNGCANCPVRSSCPAQ
3D structure
PDB6ppr Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S799 R815 R916 R918 K936 G938 K939 S940 T943 K944 Y956 S605 R621 R717 R719 K737 G739 K740 S741 T744 K745 Y757
BS02 ANP A G32 G34 S36 Y313 G9 G11 S13 Y195
BS03 SF4 A C807 R810 A1021 R1022 C1027 C1030 V1032 C1036 C613 R616 A816 R817 C822 C825 V827 C831
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0043138 3'-5' DNA helicase activity
Biological Process
GO:0000725 recombinational repair
GO:0006281 DNA repair
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005829 cytosol
GO:0033202 DNA helicase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ppr, PDBe:6ppr, PDBj:6ppr
PDBsum6ppr
PubMed31740608
UniProtA0QTR9

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