Structure of PDB 6pmh Chain A

Receptor sequence
>6pmhA (length=330) Species: 187420 (Methanothermobacter thermautotrophicus str. Delta H) [Search protein sequence]
MDEFRAYDGKCVLVTGGAGCVGSNLTGNLAKAGANVIILDNLSSSYEWNI
PEYENIEFVKGDILDDEVLKRVFKERPDYVFHLAAHFANQNSVDNPEKDL
LVNGLGILKVLEYAQLVGVERFVYSSSGCGVYGLDSKIPFEEHDISISLH
TPYQVTKLLGELYTNYFHNLYEMPIVNARFFNVFGPGEVPGKYRNVIPNF
FYWAMNQQPLPITGDGSETRDWTFVEDIVRGLMAMGVRREAIGEAINLGS
GTEHQVIEMAGIINELTENPAGVVYRPRRDWDAKTRLLSSIDKARRLLDY
EPQVSFREGLERTHRWFTENWELIRKSAEF
3D structure
PDB6pmh Structure of a UDP-GALE 4-epimerase (Mth375) from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S129 C131 G132 Y155 K159
Catalytic site (residue number reindexed from 1) S127 C129 G130 Y153 K157
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 UDP A C131 N184 N197 V198 F202 P213 I214 T215 R222 V258 R281 C129 N182 N195 V196 F200 P211 I212 T213 R220 V256 R279
BS02 AMP A G18 G21 D42 N43 S45 S46 S47 D64 I65 A86 F89 R196 G16 G19 D40 N41 S43 S44 S45 D62 I63 A84 F87 R194
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:6pmh, PDBe:6pmh, PDBj:6pmh
PDBsum6pmh
PubMed
UniProtO26475

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