Structure of PDB 6ple Chain A

Receptor sequence
>6pleA (length=96) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
PVVKINAIEVPAGAGPELEKRFAHSAHAVENSPGFLGFQLLRPVKGEERY
FVVTHWESDEAFQAWANGPAIAAHAGHRANPVATGASLLEFEVVLD
3D structure
PDB6ple Structure of aMycobacterium tuberculosisHeme-Degrading Protein, MhuD, Variant in Complex with Its Product.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.99.57: heme oxygenase (mycobilin-producing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BLA A N7 I9 R22 F23 A27 W66 H75 H78 P82 V83 A84 N6 I8 R21 F22 A26 W65 H74 H77 P81 V82 A83
BS02 BLA A A67 R79 A84 S88 L89 A66 R78 A83 S87 L88
BS03 BLA A I72 R79 I71 R78
Gene Ontology
Molecular Function
GO:0004392 heme oxygenase (decyclizing) activity
GO:0004497 monooxygenase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0042167 heme catabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Cellular Component
External links
PDB RCSB:6ple, PDBe:6ple, PDBj:6ple
PDBsum6ple
PubMed31638374
UniProtP9WKH3|MHUD_MYCTU Heme oxygenase (mycobilin-producing) (Gene Name=mhuD)

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