Structure of PDB 6pju Chain A

Receptor sequence
>6pjuA (length=171) Species: 562 (Escherichia coli) [Search protein sequence]
AGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHA
LMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKF
SGPWFGGLSGVVFALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGMA
NGAHIAGLAVGLAMAFVDSLN
3D structure
PDB6pju Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.105: rhomboid protease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M120 H150 W196 F197 G198 G199 S201 M249 A250 M28 H58 W104 F105 G106 G107 S109 M149 A150
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pju, PDBe:6pju, PDBj:6pju
PDBsum6pju
PubMed31570873
UniProtP09391|GLPG_ECOLI Rhomboid protease GlpG (Gene Name=glpG)

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