Structure of PDB 6pjr Chain A

Receptor sequence
>6pjrA (length=176) Species: 562 (Escherichia coli) [Search protein sequence]
AGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHA
LMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKF
SGPWFGGLSGVVFALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWF
MSMANGAHIAGLAVGLAMAFVDSLNA
3D structure
PDB6pjr Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
ChainA
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.21.105: rhomboid protease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F146 H150 S193 W196 F197 G198 G199 S201 S248 M249 A250 F54 H58 S101 W104 F105 G106 G107 S109 S152 M153 A154
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6pjr, PDBe:6pjr, PDBj:6pjr
PDBsum6pjr
PubMed31570873
UniProtP09391|GLPG_ECOLI Rhomboid protease GlpG (Gene Name=glpG)

[Back to BioLiP]