Structure of PDB 6pj4 Chain A

Receptor sequence
>6pj4A (length=180) Species: 562 (Escherichia coli) [Search protein sequence]
ERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFT
HALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQ
KFSGPWFGGLSGVVFALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAG
WFDLMSMANGAHIAGLAVGLAMAFVDSLNA
3D structure
PDB6pj4 Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.105: rhomboid protease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M120 F146 H150 W196 F197 G198 S248 M249 A250 M30 F56 H60 W106 F107 G108 S156 M157 A158
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pj4, PDBe:6pj4, PDBj:6pj4
PDBsum6pj4
PubMed31570873
UniProtP09391|GLPG_ECOLI Rhomboid protease GlpG (Gene Name=glpG)

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