Structure of PDB 6pim Chain A

Receptor sequence
>6pimA (length=200) Species: 9606 (Homo sapiens) [Search protein sequence]
TNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQA
PEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQ
VVVTVKDMNDNAPTIEIRGIGDVAEETAVALVQVSDRDEGENAAVTCVVA
GDVPFQLRQASEKKKYFLQTTTPLDDYTIEIVAVDSGNPPLSSTNSLKVQ
3D structure
PDB6pim Identification of an adhesive interface for the non-clustered delta 1 protocadherin-1 involved in respiratory diseases.
ChainA
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E234 E291 D322 M323 D325 D366 E19 E76 D107 M108 D110 D138
BS02 CA A N324 N326 D364 D366 N370 D423 N109 N111 D136 D138 N142 D185
BS03 CA A E234 D289 E291 D325 E19 D74 E76 D110
BS04 CA A N217 N219 D249 D251 N255 D304 N2 N4 D34 D36 N40 D89
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pim, PDBe:6pim, PDBj:6pim
PDBsum6pim
PubMed31583286
UniProtQ08174|PCDH1_HUMAN Protocadherin-1 (Gene Name=PCDH1)

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