Structure of PDB 6phy Chain A

Receptor sequence
>6phyA (length=721) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
HMGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSNSVYER
DHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFR
FVEAKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNN
DATIASYSKLDNNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTV
RRQQVEQGIFSISSNRGASGHAQTPALLLCEQGVTEDAGNVFAIQLMYSG
NFEAFVQKNQLNEVRVAIGINPENFSWKLAPEEYFETPVALVTHSDQGLT
GISHESQNFVLKHIMLSEFSKKERPILINNWEATYFDFQREKLLELADEA
KKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLISAIHERG
LQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQV
VEYLKSVLDQLLFYHDIDYIKWNMNRNITKLGNGLTYLETQMQSHQYMLG
LYELVSYLTEKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARL
PIQYGSSYLYPTISMGAHVSAVPNHQMGRMTPLETRGLVAMMGNLGYELD
LTNLSDEEKATIANQVNLYKELRPVVQLGQQYRLINPDTVSNEAAVQFNY
GNQTIVTYVRVLSVVETMETTLKLKDLDEEGLYKLQENGEVYSGAELMYA
GLTVILSQGDFLSRQYIFRKL
3D structure
PDB6phy Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.22: alpha-galactosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A Y193 W330 N474 D541 Y194 W331 N475 D542
BS02 GLA A W330 D360 D361 W405 R437 K470 N474 C519 G521 W538 D541 W331 D361 D362 W406 R438 K471 N475 C520 G522 W539 D542
BS03 GLA A K158 D160 Y283 K159 D161 Y284
BS04 GLA A S139 K158 D160 N162 S140 K159 D161 N163
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004557 alpha-galactosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0016052 carbohydrate catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6phy, PDBe:6phy, PDBj:6phy
PDBsum6phy
PubMed31591266
UniProtA0A0H2URQ6

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