Structure of PDB 6pgq Chain A

Receptor sequence
>6pgqA (length=473) Species: 562 (Escherichia coli) [Search protein sequence]
MAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFP
QVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVR
YNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALM
FNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDL
IKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLP
TFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKP
LGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVI
NAASGRQTVDEALKDAQTNAAAEFLYVVGRKKMMDAQYKCYDRMQQLPAY
QGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEK
GVWFKHPENNRTWSNYTMCNAFT
3D structure
PDB6pgq Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.
ChainA
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D77 W79 F99 D101 H121 E123 N124 R126 W128 S129 N135 D412 W414 F434 D436 H456 E458 N459 R461 W463 S464 N470
BS02 GLC A D-319 K-318 E-222 W128 D16 K17 E113 W463
BS03 GLC A W-271 D-268 R-267 E-180 P-179 Y-178 W7 W64 D67 R68 E155 P156 Y157 W342
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0015144 carbohydrate transmembrane transporter activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pgq, PDBe:6pgq, PDBj:6pgq
PDBsum6pgq
PubMed32035902
UniProtP30988|CALCR_HUMAN Calcitonin receptor (Gene Name=CALCR)

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