Structure of PDB 6pfj Chain A

Receptor sequence
>6pfjA (length=219) Species: 1520455 (Streptomyces sp. PanSC19) [Search protein sequence]
APTSLDELWRSYKETGDERLREQLILHYSPLVKYVAGRVSVGLPSNVEQA
DFVSSGVFGLIDAIEKFDVERAIKFETYAITRIRGAMIDELRALDWIPRS
VRQKARNVERAYATLEAQLRRTPSETEVAAEMDISLEDLHAVFSQLSLAN
VVALEELLHRRLLARAINTLPEREKTVVTLYYYEGLTLAEIGHVLGVTES
RVSQIHTKSVLQLRAKLAD
3D structure
PDB6pfj c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces.
ChainA
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 C2E A G61 R62 V65 G37 R38 V41 PDBbind-CN: -logKd/Ki=6.41,Kd=0.39uM
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:2000142 regulation of DNA-templated transcription initiation

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:6pfj, PDBe:6pfj, PDBj:6pfj
PDBsum6pfj
PubMed31810759
UniProtA0A3N1Q704

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