Structure of PDB 6paq Chain A

Receptor sequence

>6paqA (length=567) Species: 279238 (Novosphingobium aromaticivorans DSM 12444)

AVLRRRVVGAILMVLLGKATTLALPFAYKKAVDAMTLGGGAQPALTVALA
FVLAYALGRFSGVLFDNLRNIVFERVGQDATRHLAENVFARLHKLSLRFH
LARRTGEVTKVIERGTKSIDTMLYFLLFNIAPTVIELTAVIVIFWLNFGL
GLVTATILAVIAYVWTTRTITEWRTHLREKMNRLDGQALARAVDSLLNYE
TVKYFGAESREEARYASAARAYADAAVKSENSLGLLNIAQALIVNLLMAG
AMAWTVYGWSQGKLTVGDLVFVNTYLTQLFRPLDMLGMVYRTIRQGLIDM
AEMFRLIDTHIEVADVPNAPALVVNRPSVTFDNVVFGYDRDREILHGLSF
EVAAGSRVAIVGPSGAGKSTIARLLFRFYDPWEGRILIDGQDIAHVTQTS
LRAALGIVPQDSVLFNDTIGYNIAYGRDGASRAEVDAAAKGAAIADFIAR
LPQGYDTEVGERGLKLSGGEKQRVAIARTLVKNPPILLFDQATSALDTRT
EQDILSTMRAVASHRTTISIAHRLSTIADSDTILVLDQGRLAEQGSHLDL
LRRDGLYAEMWARQAAE

3D structure

• PDB: 6paq A structural framework for unidirectional transport by a bacterial ABC exporter.
• Chain: A
• Resolution: 3.301 Å

Enzymatic activity

• Enzyme Commision number: 7.-.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ATP	A	Y370 D371 R374 S396 G397 A398 G399 K400 S401 T402 H554	Y338 D339 R342 S364 G365 A366 G367 K368 S369 T370 H522
BS02	ATP	A	K497 S499 G501	K465 S467 G469

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0042626 ATPase-coupled transmembrane transporter activity
• GO:0140359 ABC-type transporter activity

Biological Process

• GO:0006811 monoatomic ion transport
• GO:0046689 response to mercury ion
• GO:0055085 transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:6paq, PDBe:6paq, PDBj:6paq
• PDBsum: 6paq
• PubMed: 32703810
• UniProt: Q2G506|ATM1_NOVAD ATM1-type heavy metal exporter (Gene Name=atm1)