Structure of PDB 6pag Chain A

Receptor sequence
>6pagA (length=277) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPW
VEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGC
DLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAAR
AAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPS
GQEQRYTCHMQHEGLQEPLTLSWEPSS
3D structure
PDB6pag Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.
ChainA
Resolution2.501 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 D9 Y59 R62 E63 K66 Y67 Q70 V76 S77 N80 Y84 D114 T143 A150 Y159 W167 Y171 Y6 D8 Y58 R61 E62 K65 Y66 Q69 V75 S76 N79 Y83 D113 T142 A149 Y158 W166 Y170
External links
PDB RCSB:6pag, PDBe:6pag, PDBj:6pag
PDBsum6pag
PubMed33846289
UniProtP10321|HLAC_HUMAN HLA class I histocompatibility antigen, C alpha chain (Gene Name=HLA-C)

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