Structure of PDB 6pa7 Chain A

Receptor sequence
>6pa7A (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB6pa7 Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B.
ChainA
Resolution2.94 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R40 Y41 P43 V46 A47 R49 R63 K64 L65 P66 R69 R4 Y5 P7 V10 A11 R13 R27 K28 L29 P30 R33
BS02 dna A R40 Y41 R42 T45 R72 R83 F84 Q85 R116 V117 T118 M120 R4 Y5 R6 T9 R36 R47 F48 Q49 R80 V81 T82 M84
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:6pa7, PDBe:6pa7, PDBj:6pa7
PDBsum6pa7
PubMed32968275
UniProtP84233|H32_XENLA Histone H3.2

[Back to BioLiP]