Structure of PDB 6p4k Chain A

Receptor sequence
>6p4kA (length=514) Species: 223997 (Murine norovirus 1) [Search protein sequence]
QDLVPAAVEQAVPIQPVAGAALAAPAAGQINQIDPWIFQNFVQCPLGEFS
ISPRNTPGEILFDLALGPGLNPYLAHLSAMYTGWVGNMEVQLVLAGNAFT
AGKVVVALVPPYFPKGSLTTAQITCFPHVMCDVRTLEPIQLPLLDVRRVL
WHATQDQEESMRLVCMLYTPLRTNSPGDESFVVSGRLLSKPAADFNFVYL
TPPIERTIYRMVDLPVIQPRLCTHARWPAPVYGLLVDPSLPSNPQWQNGR
VHVDGTLLGTTPISGSWVSCFAAEAAYEFQSGTGEVATFTLIEQDGSAYV
PGDRAAPLGYPDFSGQLEIEVQTETTKTGDKLKVTTFEMILGPTTNADQA
PYQGRVFASVTAAASLDLVDGRVRAVPRSIYGFQDTIPEYNDGLLVPLAP
PIGPFLPGEVLLRFRTYMRQIDTADAAAEAIDCALPQEFVSWFASNAFTV
QSEALLLRYRNTLTGQLLFECKLYNEGYIALSYSGSGPLTFPTDGIFEVV
SWVPRLYQLASVGS
3D structure
PDB6p4k Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 TCH A G314 R390 R392 G296 R372 R374
BS02 TCH A Y250 Y435 M436 R437 Y232 Y417 M418 R419
Gene Ontology
Biological Process
GO:0019049 virus-mediated perturbation of host defense response
Cellular Component
GO:0044423 virion component

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6p4k, PDBe:6p4k, PDBj:6p4k
PDBsum6p4k
PubMed31341042
UniProtQ2V8W4

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