Structure of PDB 6p2s Chain A

Receptor sequence
>6p2sA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIFKTNTQTDRCSLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB6p2s ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 D9 N63 I66 F67 N70 T73 D74 C76 S77 N80 Y84 S97 Y99 Y116 Y123 T143 W147 Q155 D156 Y159 Y171 Y7 D9 N63 I66 F67 N70 T73 D74 C76 S77 N80 Y84 S97 Y99 Y116 Y123 T143 W147 Q155 D156 Y159 Y171
External links
PDB RCSB:6p2s, PDBe:6p2s, PDBj:6p2s
PDBsum6p2s
PubMed31601650
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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