Structure of PDB 6p08 Chain A

Receptor sequence
>6p08A (length=252) Species: 1409 (Bacillus sp. (in: firmicutes)) [Search protein sequence]
NGPIIMTREERMKIVHEIKERILDKYGDDVKAIGVYGSLGRQTDGPYSDI
DMMCVMSTEEAEFSHEWTTGEWKVEVNFDSEEILLDYASQVESDWPLTHG
QFFSILPIYDSGGYLEKVYQTAKSVEAQKFHDAICALIVEELFEYAGKWR
NIRVQGPTTFLPSLTVQVAMAGAMLIGLHHRICYTTSASVLTEAVKQSDL
PSGYDHLCQFVMSGQLSDSEKLLESLENFWNGIQEWTERHGYIVDVSKRI
PF
3D structure
PDB6p08 Catch and Release": a Variation of the Archetypal Nucleotidyl Transfer Reaction
ChainA
Resolution2.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NMY A Y37 E67 E76 D80 Y88 Q102 Y36 E66 E75 D79 Y87 Q101
BS02 MG A D50 D52 D49 D51
BS03 MG A D50 D52 D49 D51
BS04 AMP A E145 K149 E144 K148
BS05 AMP A Y37 G38 D52 T99 Y36 G37 D51 T98
BS06 NMY A E141 E145 E140 E144
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function

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Biological Process
External links
PDB RCSB:6p08, PDBe:6p08, PDBj:6p08
PDBsum6p08
PubMed
UniProtP05058|KANU_BACSP Kanamycin nucleotidyltransferase (Gene Name=knt)

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