Structure of PDB 6ov8 Chain A

Receptor sequence
>6ov8A (length=429) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
NAMTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAA
RKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVVWPDLDDAQRQ
ELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITK
GEDLREQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGIT
FDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCA
DNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPEM
IIDAATLTGAAKTALGNDYHALFSFDDALAGRLLASAAQENEPFWRLPLA
EFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGWLHIDCS
ATYRKAPVEQWSAGATGLGVRTIANLLTA
3D structure
PDB6ov8 Comparison of metal-bound and unbound structures of aminopeptidase B proteins from Escherichia coli and Yersinia pestis.
ChainA
Resolution2.61 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.11.23: PepB aminopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A K195 D200 D218 E279 K197 D202 D220 E281
BS02 MN A D200 K207 D277 E279 D202 K209 D279 E281
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0030145 manganese ion binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0019538 protein metabolic process
GO:0043171 peptide catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ov8, PDBe:6ov8, PDBj:6ov8
PDBsum6ov8
PubMed32306515
UniProtP37095|PEPB_ECOLI Peptidase B (Gene Name=pepB)

[Back to BioLiP]