Structure of PDB 6ou1 Chain A

Receptor sequence
>6ou1A (length=260) Species: 9606 (Homo sapiens) [Search protein sequence]
GCGELVWVGEPVTLRTAETITGKYGVWMRDPKPVYPYTQETTWRIDTVGT
DVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYNGSLYFQGAGSRT
VIRYDLKTETVKAEKEIPGAGYHGQYPYSWGGYTDIDLAVDENGLWVIYS
TNQAKGNIVLSKLNPETLEVEQTWETNIRKQSVANAFIICGTLYTVSSYT
SADATVNFAYDTNTGTSKYLDIPFKNRYKYNSMIDYNPLERKLFAWDNGH
MVTYDIKLSK
3D structure
PDB6ou1 Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations.
ChainA
Resolution1.878 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D380 N428 A429 I477 D478 D137 N185 A186 I234 D235
External links
PDB RCSB:6ou1, PDBe:6ou1, PDBj:6ou1
PDBsum6ou1
PubMed31270212
UniProtQ99972|MYOC_HUMAN Myocilin (Gene Name=MYOC)

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