Structure of PDB 6os1 Chain A

Receptor sequence
>6os1A (length=381) Species: 562,9606 [Search protein sequence]
IKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSF
NLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLAS
LPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLI
ILTSYTLIWKALKKAYDLEDNWETLNDNLKVIEKADNAAQVKDALTKMRA
AALDAQKARHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKKNKPRNDD
IFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPIT
ICIAYFNNCLNPLFYGFLGKKFKRYFLQLLK
3D structure
PDB6os1 Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
ChainA
Resolution2.794 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D17 W84 Y87 V108 R167 A181 Y184 K199 D1263 D1281 M1284 I1288 D7 W74 Y77 V98 R157 A171 Y174 K189 D326 D344 M347 I351
BS02 CLR A I43 L1316 I33 L379
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004945 angiotensin type II receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0019229 regulation of vasoconstriction
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:6os1, PDBe:6os1, PDBj:6os1
PDBsum6os1
PubMed32079768
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P30556

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