Structure of PDB 6os0 Chain A

Receptor sequence
>6os0A (length=395) Species: 562,9606 [Search protein sequence]
DGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMK
LKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASV
SFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGL
ASLPAIIHRNVFFIENTNITVCAFHYESQNLPIGLGLTKNILGFLFPFLI
ILTSYTLIWKALKKAYDLEDNWETLNDNLKVIEKADNAAQVKDALTKMRA
AALDAQKATPPPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQL
KTTRAEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGII
RDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQL
3D structure
PDB6os0 Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q15 D17 R23 W84 Y87 Y92 S109 R167 A181 F182 Y184 K199 D1263 D1281 M1284 Q7 D9 R15 W76 Y79 Y84 S101 R159 A173 F174 Y176 K189 D342 D360 M363
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004945 angiotensin type II receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0019229 regulation of vasoconstriction
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:6os0, PDBe:6os0, PDBj:6os0
PDBsum6os0
PubMed32079768
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P30556

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