Structure of PDB 6oov Chain A

Receptor sequence
>6oovA (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
CGRTSCHLPRDVLTRACAYQDRRGQQRLPEWRDPDKYCPSYNKSPQSNSP
VLLSRLHFEKDADSSERIIAPMRWGLVPSWFKESDPSKLQFNTTNCRSDT
VMEKRSFKVPLGKGRRCVVLADGFYEWQRCQGTNQRQPYFIYFPQKVWDN
WRLLTMAGIFDCWEPPEGGDVLYSYTIITVDSCKGLSDIHHRMPAILDGE
EAVSKWLDFGEVSTQEALKLIHPTENITFHAVSSVVNNSRNNTPECLAPV
3D structure
PDB6oov Crystal structure of HMCES SRAP domain in complex with palindromic 3' overhang DNA
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.-.-
4.-.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A W81 F92 N93 N96 R98 K105 R106 S107 T199 H210 R212 W80 F91 N92 N95 R97 K104 R105 S106 T179 H190 R192
Gene Ontology
Molecular Function
GO:0003697 single-stranded DNA binding
Biological Process
GO:0006974 DNA damage response
GO:0106300 protein-DNA covalent cross-linking repair

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Molecular Function

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Biological Process
External links
PDB RCSB:6oov, PDBe:6oov, PDBj:6oov
PDBsum6oov
PubMed
UniProtQ96FZ2|HMCES_HUMAN Abasic site processing protein HMCES (Gene Name=HMCES)

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