Structure of PDB 6oog Chain A

Receptor sequence
>6oogA (length=252) Species: 6204 (Taenia solium) [Search protein sequence]
PHMTRKLFVGGNWKMNGSYSHINTFFDTLQKADTDPNADIVIGVPACYLK
YAQDKAPKGIKIAAENCYKVGSGAFTGEISTEMIKDCGCEWVILGHSERR
HIFGESNELIGEKVKHALDSGLNVIPCIGELLSEREAGKTNDVCFAQMDA
IAKNVPSKEAWDKVVIAYEPVWAIGTGKTATPAQAQEVHKVVRDWIRKHV
DAGIADKVRILYGGSVTASNAKDLGTQPDVDGFLVGGASLKPDFITIINA
RR
3D structure
PDB6oog Crystal structures of Triosephosphate Isomerases from Taenia solium and Schistosoma mansoni provide insights for vaccine rationale and drug design against helminth parasites.
ChainA
Resolution2.02 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N10 K12 H94 E96 E167 G173 S213
Catalytic site (residue number reindexed from 1) N12 K14 H96 E98 E169 G175 S215
Enzyme Commision number 5.3.1.1: triose-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PGA A K12 H94 E167 I172 G173 S213 G234 G235 K14 H96 E169 I174 G175 S215 G236 G237
Gene Ontology
Molecular Function
GO:0004807 triose-phosphate isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0019563 glycerol catabolic process
GO:0046166 glyceraldehyde-3-phosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:6oog, PDBe:6oog, PDBj:6oog
PDBsum6oog
PubMed31923219
UniProtQ9GTX8|TPIS_TAESO Triosephosphate isomerase

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