Structure of PDB 6ony Chain A

Receptor sequence
>6onyA (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
GRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMD
MGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKI
FLQKVASMPQEEQE
3D structure
PDB6ony Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HWV A W97 P98 V103 D104 L108 L110 N156 I162 W25 P26 V31 D32 L36 L38 N84 I90 BindingDB: Ki=4.6nM
External links
PDB RCSB:6ony, PDBe:6ony, PDBj:6ony
PDBsum6ony
PubMed31969702
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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