Structure of PDB 6om1 Chain A

Receptor sequence
>6om1A (length=592) Species: 9606 (Homo sapiens) [Search protein sequence]
FNLDVDSPAEYSGPEGSYFGFAVDFFVPSSSRMFLLVGAPKANTTQPGIV
EGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSK
QDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADG
QGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYS
IKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLG
MVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFM
DRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLD
QDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGC
PPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY
PSILNQDNKTCSLPLKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLK
QKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLESEFRDKLTPI
TIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLTGG
3D structure
PDB6om1 General structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
ChainA
Resolution2.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D230 N232 D234 I236 D238 D229 N231 D233 I235 D237
BS02 CA A D284 N286 D288 Y290 D292 D283 N285 D287 Y289 D291
BS03 CA A D349 D351 D353 F355 D357 D348 D350 D352 F354 D356
BS04 CA A D414 D416 N418 Y420 D422 D413 D415 N417 Y419 D421
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6om1, PDBe:6om1, PDBj:6om1
PDBsum6om1
PubMed31792290
UniProtP06756|ITAV_HUMAN Integrin alpha-V (Gene Name=ITGAV)

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