Structure of PDB 6oh9 Chain A

Receptor sequence
>6oh9A (length=452) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
DKHGKFLVFFGTFVDTPKLGELRIREKTSVGVLNGIIRFVNRNSLDPVKD
CLDHDSSLSPEDVTVVDINNSFYFPGFVDTHNHVSQYPNVGVFGNSTLLD
WLEKYTFPIEAALANENIAREVYNKVISKTLSHGTTTVAYYNTIDLKSTK
LLAQLSSLLGQRVLVGKVCMDTNGPEYYIEDTKTSFESTVKVVKYIRETI
CDPLVNPIVTPRFAPSCSRELMQQLSKLVKDENIHVQTHLSENKEEIQWV
QDLFPECESYTDVYDKYGLLTEKTVLAHCIHLTDAEARVIKQRRCGISHC
PISNSSLTSGECRVRWLLDQGIKVGLGTDVSAGHSCSILTTGRQAFAVSR
HLAMRETDHAKLSVSECLFLATMGGAQVLRMDETLGTFDVGKQFDAQMID
TNAPGSNVDMFHWQLKNPPLLTNEDIIAKWFFNGDDRNTTKVWVAGQQVY
QI
3D structure
PDB6oh9 Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.3: guanine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H100 H102 H258 D348 H81 H83 H239 D329
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008892 guanine deaminase activity
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872 metal ion binding
Biological Process
GO:0006147 guanine catabolic process
GO:0046098 guanine metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6oh9, PDBe:6oh9, PDBj:6oh9
PDBsum6oh9
PubMed31283204
UniProtQ07729|GUAD_YEAST Probable guanine deaminase (Gene Name=GUD1)

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