Structure of PDB 6ogy Chain A

Receptor sequence
>6ogyA (length=1053) Species: 28875 (Rotavirus A) [Search protein sequence]
GKYNLILSEYLSFIYNSQSAVQIPIYYSSNSENATLLSILSYSYDKYNAV
ERKLVKYAKGKPLEADLTVNELDYENNKITSELFPTAEEYTDLLMDPAIL
TSLSSNLNAVMFWLEKHENDVAEKLKIYKRRLDLFTIVASTVNKYGVPRH
NAKYRYEYEVMKDKPYYLVTWANSSIEMLMSVFSHEDYLIARELIVLSYS
NRSTLAKLVSSPMSILVALVDINGTFITNEELELEFSNKYVRAIVPDQTF
DELKQMLDNMRKAGLTDIPKMIQDWLVDCSIEKFPLMAKIYSWSFHVGFR
KQKMLDAALDQLKTEYTEDVDDEMYREYTMLIRDEVVKMLEEPVKHDDHL
LQDSELAGLLSMSSASNGESRQLKFGRKTIFSTKKNMHVMDDMANGRYTP
GIIPPVNVDKPIPLGRRDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAK
HTREYAEFYSQSNQLLSYGDVTRFLSNNSMVLYTDVSQWDSSQHNTQPFR
KGIIMGLDMLANMTNDARVIQTLNLYKQTQINLMDSYVQIPDGNVIKKIQ
YGAVASGEKQTKAANSIANLALIKTVLSRISNKYSFATKIIRVDGDDNYA
VLQFNTEVTKQMVQDVSNDVRETYARMNTKVKALVSTVGIEIAKRYIAGG
KIFFRAGINLLNNEKKGQSTQWDQAAVLYSNYIVNRLRGFETDREFILTK
IMQMTSVAITGSLRLFPSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQ
RAFMSLSSQKSGIADEIAASSTFKNYVSRLSEQLLFSKNNIVSRGIALTE
KAKLNSYAPISLEKRRAQISALLTMLQKPVTFKSSKITINDILRDIKPFF
TVNEAHLPIQYQKFMPTLPDNVQYIIQCIGSRTYQIEDDGSKSAISRLIS
KYSVYKPSIEELYKVISLHENEIQLYLISLGIPKIDADTYVGSKIYSQDK
YRILESYVYNLLSINYGCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHL
YAKLEVINHAIKNGSWISLFCNYPKSEMIKLWKKMWNITSLRSPYTNANF
FQD
3D structure
PDB6ogy In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Y16 D80 K81 Y82 S137 S140 R184 H185 Y189 Q738 R749 Y15 D45 K46 Y47 S102 S105 R149 H150 Y154 Q703 R714
BS02 rna A K413 F416 T418 K419 I798 Y842 K378 F381 T383 K384 I763 Y807
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ogy, PDBe:6ogy, PDBj:6ogy
PDBsum6ogy
PubMed31101900
UniProtG0YZJ9

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