Structure of PDB 6oea Chain A

Receptor sequence
>6oeaA (length=258) Species: 9606 (Homo sapiens) [Search protein sequence]
CGRTSCHLPRDVLTRACAYQDRRGQQRLPEWRDPDKYCPSYNKSPQSNSP
VLLSRLHFEKDADSSERIIAPMRWGLVPSWFKESDPSKLQFNTTNCRSDT
VMEKRSFKVPLGKGRRCVVLADGFYEWQRCQGTNQRQPYFIYFPQIKSPE
NWEKVWDNWRLLTMAGIFDCWEPPEGGDVLYSYTIITVDSCKGLSDIHHR
MPAILDGEEAVSKWLDFGEVSTQEALKLIHPTENITFHAVSSVVNNSRNN
TPECLAPV
3D structure
PDB6oea Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.-.-
4.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A W81 F92 N93 N96 R98 K105 R106 S107 F108 T199 H210 H211 R212 W80 F91 N92 N95 R97 K104 R105 S106 F107 T187 H198 H199 R200
BS02 dna A W81 R106 K109 W80 R105 K108
Gene Ontology
Molecular Function
GO:0003697 single-stranded DNA binding
Biological Process
GO:0006974 DNA damage response
GO:0106300 protein-DNA covalent cross-linking repair

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Molecular Function
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Biological Process
External links
PDB RCSB:6oea, PDBe:6oea, PDBj:6oea
PDBsum6oea
PubMed31235913
UniProtQ96FZ2|HMCES_HUMAN Abasic site processing protein HMCES (Gene Name=HMCES)

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