Structure of PDB 6o9c Chain A

Receptor sequence
>6o9cA (length=279) Species: 9606 (Homo sapiens) [Search protein sequence]
SGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRA
PWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY
GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEA
AHEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWELSS
3D structure
PDB6o9c An engineered antibody fragment targeting mutant beta-catenin via major histocompatibility complex I neoantigen presentation.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 N66 D77 Y84 Y99 D116 T143 K146 W147 E152 Y159 W167 Y171 Y8 E64 N67 D78 Y85 Y100 D117 T144 K147 W148 E153 Y160 W168 Y172
External links
PDB RCSB:6o9c, PDBe:6o9c, PDBj:6o9c
PDBsum6o9c
PubMed31690625
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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