Structure of PDB 6o9b Chain A

Receptor sequence
>6o9bA (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]
SGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRA
PWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY
GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEA
AHEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWELS
3D structure
PDB6o9b An engineered antibody fragment targeting mutant beta-catenin via major histocompatibility complex I neoantigen presentation.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 E63 N66 T73 D77 Y84 Y99 R114 D116 T143 K146 W147 E152 Q155 Y159 W167 Y171 Y8 E64 N67 T74 D78 Y85 Y100 R115 D117 T144 K147 W148 E153 Q156 Y160 W168 Y172
External links
PDB RCSB:6o9b, PDBe:6o9b, PDBj:6o9b
PDBsum6o9b
PubMed31690625
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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