Structure of PDB 6o8g Chain A

Receptor sequence

>6o8gA (length=564) Species: 1395 ([Bacillus] caldotenax)

EGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTISN
VIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVCYYDYYKINDE
IDKLRHSATSALFERRDVIIVASVSSIYGLGSPEEYRELVVSLRVGMEIE
RNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHSIRVEFFG
DEIERIREVDALTGEVLGEREHVAIFPASHFVTREEKMRLAIQNIEQELE
ERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFSSGIENYSRHLALRPP
GSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMYNGDRARKQVLVDHGFRL
PSALDNRPLTFEEFEQKINQIIYVSATPGPYELEHSPGVVEQIIRPTGLL
DPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEA
GIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVA
ILDADKEGFLRSERSLIQTIGRAARNANGHVIMYADTITKSMEIAIQETK
RRRAIQEEYNRKHG

3D structure

• PDB: 6o8g Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System.
• Chain: A
• Resolution: 2.64 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	N66 K67 C91 S141 Y146 R289 Q346 R357 K358 L361 F366 T454 K455 H476 S477 R484 I502 N503 L504 F527	N65 K66 C90 S123 Y128 R271 Q328 R339 K340 L343 F348 T436 K437 H458 S459 R466 I484 N485 L486 F509
BS02	dna	A	Y292 P345 G349 G353 R357 G526 F527 S530	Y274 P327 G331 G335 R339 G508 F509 S512
BS03	ADP	A	Y11 Q14 Q17 G42 T43 G44 K45 F47 R543	Y10 Q13 Q16 G41 T42 G43 K44 F46 R525

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006289 nucleotide-excision repair

Cellular Component

• GO:0009380 excinuclease repair complex

External links

• PDB: RCSB:6o8g, PDBe:6o8g, PDBj:6o8g
• PDBsum: 6o8g
• PubMed: 31549070
• UniProt: P56981|UVRB_BACCA UvrABC system protein B (Gene Name=uvrB)