Structure of PDB 6o3g Chain A

Receptor sequence

>6o3gA (length=226) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVQSGGEVKRPGSSVTVSCKATGGTFSTLAFNWVRQAPGQGPEWMGG
IVPLFSIVNYGQKFQGRLTIRADKSTTTVFLDLSGLTSADTATYYCAREG
EGWFGKPLRAFEFWGQGTVITVSSASTKGPSVFPLAPSSKSTSGGTAALG
CLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSL
GTQTYICNVNHKPSNTKVDKKVEPKS

3D structure

PDB

6o3g An MPER antibody neutralizes HIV-1 using germline features shared among donors.

Chain

Resolution

3.645 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	A33 N35 W47 G50 I51 V52 I56 N58 E95 F100 G100A K100B P100C R100E	A33 N35 W47 G50 I51 V52 I57 N59 E99 F104 G105 K106 P107 R109

External links

PDB	RCSB:6o3g, PDBe:6o3g, PDBj:6o3g
PDBsum	6o3g
PubMed	31772165

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